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N-Desmethyl ponatinib

Detailed product information, standard pack sizes and direct quote request for analytical and research use.

Product summary

CAT No. HX-EK-02100
CAS 943319-87-7
Metabolites
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Product information

Product NameN-Desmethyl ponatinib
CAT No.HX-EK-02100
CAS No.943319-87-7
CategoryMetabolites
Parent APIPonatinib
Molecular FormulaC₂₈H₂₅F₃N₆O
Molecular Weight518.53
Stock StatusIn Stock
ApplicationPonatinib Active Metabolite AP24567(M42) is a research reagent applied in pharmaceuticals and cancer treatment. Ponatinib Active Metabolite AP24567(M42) is an analog of Ponatinib (P688250) which is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib (P688250) is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor It is a COVID19-related research product.

Available pack sizes

1 mg2 mg5 mg10 mg25 mg

Analytical and research use

N-Desmethyl ponatinib is listed under Metabolites and may be used for analytical research, method development, method validation, impurity profiling and routine quality control workflows. Documentation such as COA and MSDS can be requested during enquiry.

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