Atracurium Impurity F

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• Catalog Number : HXDG-00005
• Category : Impurities
• CAS Number : 41431-32-7
• Molecular Weight : 499.38
• Molecular Formula : C22H30NIO4
• Application Notes : (R)-N-Methyl-Laudanosine Iodide is a derivative of Laudanosine (L178525) a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
• References :Canfell, P., et al.: Drug Metab. Dispos., 14, 703 (1986), Anselmi, E., et al.: J. Pharm. Pharmacol., 44, 337 (1992), Bohrer, H., et al.: Pharmacol. Toxicol., 73, 137 (1993),
• Synonym : (1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium benzenesulfonate