BODIPY TMR Phosphatidylinositol 3,4-bisphosphate

Product Details

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• Catalog Number : HXAS-00024
• Category : Phosphoinositols
• CAS Number : NA
• Molecular Weight : 1704.78
• Molecular Formula : C78H147BF2N9O22P3
• Application Notes : Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.
• References :
• Synonym : 2,2-difluoro-11-(2-{[5-({6-[(2R)-2-(hexanoyloxy)-3- {[(1S,2R,3R,4S,5S,6S)-2,3,6-trihydroxy-4,5- bis(phosphonatooxy)cyclohexyl phosphonato]oxy}propoxy]-6- oxohexyl}carbamoyl)pentyl]carbamoyl}ethyl)-4-(4- methoxyphenyl)-10,12-dimethyl